From: Circulating tumour DNA for monitoring colorectal cancer—a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection
Factor
Odds ratio (95% CI)
P value
Stage
< 0.001
I
1 (reference)
II
12.5 (4.3–36.6)
III
16.6 (5.7–48)
IV
92.1 (16.5–513.8)
Location
0.004
Proximal colon
Distal colon and rectum
3.0 (1.4–6.2)