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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Circulating tumour DNA for monitoring colorectal cancer—a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection

Fig. 3

The case-by-case relationship between methylation in tissue and ctDNA positivity according to cancer stage. The top grey panel shows ctDNA positivity; open diamonds, ctDNA negative; black/white, BCAT1 positive only; white/red, IKZF1 positive only; and black/red, ctDNA methylated in both genes. The bottom panel shows graphical representation of methylation levels in cancer tissues (closed circles: black, BCAT1; red, IKZF1). Tissues with no detectable BCAT1 and/or IKZF1 are indicated with open circles

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