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Table 2 Univariate and multivariate analyses of prognostic factors for complete remission in whole-cohort and non-APL-AML patients

From: H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia

  Univariate analysis Multivariate analysis
Odds ratio (95% CI) P value Odds ratio (95% CI) P value
Whole-cohort AML
Age 0.119 (0.054–0.262) < 0.001 0.162 (0.069–0.379) < 0.001
WBC 0.269 (0.126–0.575) 0.001 0.505 (0.204–1.253) 0.140
Karyotype classifications 0.214 (0.112–0.408) < 0.001 0.269 (0.139–0.519) < 0.001
H19 expression 0.370 (0.189–0.726) 0.004 0.416 (0.185–0.935) 0.034
Non-APL AML
Age 0.164 (0.069–0.392) < 0.001 0.199 (0.079–0.502) 0.001
WBC 0.353 (0.153–0.819) 0.015 0.522 (0.198–1.378) 0.189
Karyotype classifications 0.316 (0.145–0.691) 0.004 0.297 (0.129–0.687) 0.005
H19 expression 0.361 (0.164–0.791) 0.011 0.306 (0.123–0.762) 0.011
  1. Variables were composed of age (≤ 60 vs. > 60 years), WBC (≥ 30 × 109 vs. < 30 × 109/L), karyotype classifications (favorable vs. intermediate vs. poor), and H19 expression (low vs. high). The multivariate analysis included variables with P < 0.100 in univariate analysis for complete remission
  2. AML acute myeloid leukemia, APL acute promyelocytic leukemia, WBC white blood cells, CI confidence interval