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Table 1 Baseline characteristics of HyperGen study participants

From: Epigenome-wide association study of metabolic syndrome in African-American adults

  MetS+ (N = 284) MetS− (N = 330) p value*
Age† 52.0 ± 10.0 46.0 ± 11.0 < 0.0001
High WC/obesity
 WC (cm)† 112.4 ± 16.6 96.6 ± 16.9 < 0.0001
 BMI† 35.4 ± 8.1 29.8 ± 7.4 < 0.0001
Elevated triglycerides
 Triglycerides (mg/dL)§ 125.5 ± 83.5 77.0 ± 42.8 < 0.0001
Reduced HDL cholesterol
 HDL cholesterol (mg/dL)† 46.9 ± 12.5 58.8 ± 15.5 < 0.0001
Elevated blood pressure
 DBP (mmHg)† 75.3 ± 11.8 75.5 ± 13.3 0.8
 SBP (mmHg)† 136 ± 22.8 127.6 ± 23.7 < 0.0001
 Hypertension (%) 86.6 48.9 < 0.0001
Elevated fasting glucose
 Fasting glucose (mg/dL)† 133.8 ± 69.9 94.2 ± 31.2 < 0.0001
Metabolic components** (%)
 0 0 17.3  
 1 0 33.9  
 2 0 48.8  
 3 51.4 0  
 4 28.2 0  
 5 20.4 0  
  1. BMI body mass index, HDL high-density lipoprotein, LDL low-density lipoprotein, DBP diastolic blood pressure, SBP systolic blood pressure
  2. †Presented as mean (standard deviation) for normal continuous characteristics
  3. §Presented as median (interquartile range) for non-parametric continuous characteristics
  4. *Significance determined using chi-square test for categorical, t test for continuous, or kruskal.test test for non-parametric continuous variables
  5. **Metabolic components are high waist circumference (WC), elevated triglycerides, reduced HDL cholesterol, elevated blood pressure, and elevated fasting glucose
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Clinical Epigenetics

ISSN: 1868-7083

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