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Table 2 Disease-free survival analysis by Cox regression in TCGA patients

From: A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97

DFS

Multivariable analysis

HR

95% CI for HR

p value

mir152

 mir152 expression levela

0.228

0.072–0.722

0.012

 Age

0.999

0.970–1.028

0.928

 Gleason Scoreb

  6

  

< 0.0001

  7

5.528

0.754–40.536

0.093

  8

11.104

1.455–84.709

0.020

  9

23.559

3.247–170.946

0.002

  10

24.146

1.502–388.242

0.025

TMEM97

TMEM97 expression levela

1.007

0.550–1844

0.980

 Age

1.000

0.971–1.029

0.978

 Gleason Scoreb

  6

  

< 0.0001

  7

5.369

0.732–39.373

0.098

  8

10.978

1.438–83.790

0.002

  9

23.087

3.179–167.641

0.005

  10

30.812

2.786–340.785

0.978

NOL4

NOL4 expression levela

0.778

0.392–1.545

0.473

 Age

1.000

0.972–1.029

0.979

 Gleason Scoreb

  6

  

< 0.0001

  7

5.309

0.724–38.935

0.101

  8

10.967

1.438–83.629

0.021

  9

22.911

3.158–166.213

0.002

  10

31.102

2.811–344.117

0.005

  1. p value significant when p < 0.05
  2. HR hazard ratio, CI confidence interval.
  3. aReference group: high expression level
  4. bReference group: Gleason Score 6