Table 1 Demographic and clinicopathological information of participated patients

Age (years, mean ± SD)

54.98 ± 17.63

63.23 ± 11.58

< 0.0001

53.77 ± 16.04

61.07 ± 9.66

0.0001

Gender

0.38

0.20

 Male (%)

65.2%(60/92)

70.1% (131/187)

69.4% (75/108)

77.9% (67/86)

 Female (%)

34.8%(32/92)

29.9% (56/187)

30.6% (33/108)

22.1% (19/86)

Smoking status

0.35

0.25

 Never

25.6% (23/90)

22.4% (37/165)

26.9% (29/108)

19.8% (17/86)

 Current

21.1% (19/90)

30.3% (50/165)

16.7% (18/108)

24.4% (21/86)

 Ex-smoker

53.3%(48/90)

47.3% (78//165)

56.5% (61/108)

55.8% (48/86)

 OSCC

n/a

50.8% (95/187)

n/a

50.6% (42/83)

 OPSCC

n/a

23.5% (44/187)

n/a

33.7% (28/83)

 LSCC

n/a

25.7% (48/187)

n/a

15.7% (13/83)

 Positive

n/a

37.9% (25/66)

n/a

n/a

 Negative

n/a

62.1% (41/66)

n/a

n/a

 T1

n/a

24.7% (46/186)

n/a

25.6% (20/78)

 T2

n/a

26.3% (49/186)

n/a

33.3% (26/78)

 T3

n/a

22.1% (41/186)

n/a

14.1% (11/78)

 T4

n/a

26.9% (50/186)

n/a

26.9% (21/78)

 N0

n/a

41.9% (78/186)

n/a

36.8% (28/76)

 N1

n/a

19.9% (37/186)

n/a

7.9% (6/76)

 N2

n/a

35.5% (66/186)

n/a

52.6% (40/76)

 N3

n/a

2.7% (5/186)

n/a

2.6% (2/76)

 I

n/a

18.3%(34/186)

n/a

13.2%(10/76)

 II

n/a

10.8%(20/186)

n/a

17.1%(13/76)

 III

n/a

31.7%(59/186)

n/a

22.4%(17/76)

 IV

n/a

39.3%(73/186)

n/a

47.4%(36/76)