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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states

Fig. 4

CpG methylation analysis. a Percentage of 5′-methylcytosine content in genomic DNA in patients with HIV versus non-HIV infected individuals. Horizontal bars represent mean values and boxes IQR; (b) correlation plot between global DNA methylation and CD4+/CD8+ T cell ratio (Pearson correlation test); and (c) correlation plot between global DNA methylation and DNMT1 expression in the group of HIV-1 controllers (due to the nature of variables, the nonparametric Spearman correlation test was used)

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