Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer

Table 5 Clinicopathological parameters of urine samples analyzed in this study by pyrosequencing

Categorization	n	% analyzable
Controls:	51
Age (median 69)
≤ 69 years	28	54.9
> 69 years	23	45.1
Gender
Male	48	94.1
Female	3	5.9
Diagnosis
Disease-free	3	5.9
Cystitis	5	9.8
Benign prostatic hyperplasia	13	25.5
Prostate cancer	21	41.2
Testicular tumor	6	11.8
Other	3	5.9
BLCA asscociated^a	52
Age (median 71)
≤ 71 years	27	51.9
> 71 years	25	48.1
Gender
Male	42	80.8
Female	10	19.2
Histological tumor grade^b
Low grade	19	36.5
High grade	30	57.7
NA	3	5.8
Tumor stage^b
pTa	21	40.4
pTis	3	5.8
pT1	11	21.2
pT2	8	15.4
pT3	7	13.5
pT4	2	3.8

^aOnly urine samples of patients preoperatively diagnosed with primary bladder cancer (UC, without any other malignancy) were included
^bAccording to WHO 2004 classification

ISSN: 1868-7083