|
Overall survival (OS)
|
---|
|
n
a
|
Events
|
p valueb
|
---|
Parameter:
|
RBBP8 methylationc
|
RBBP8 Mlow
|
262
|
103
|
0.039
|
RBBP8 Mhigh
|
85
|
24
|
Gender
|
Male
|
253
|
91
|
0.920
|
Female
|
94
|
36
|
Histological tumor graded
|
Low grade
|
15
|
0
|
0.066
|
High grade
|
329
|
127
|
Tumor stage
|
pT1-pT2
|
105
|
23
|
≤ 0.001
|
pT3-pT4
|
214
|
94
|
pN status
|
Negative
|
207
|
53
|
≤ 0.001
|
Nositive
|
111
|
63
|
pM status
|
Negative
|
168
|
52
|
0.004
|
Positive
|
7
|
5
|
- Significant p values are in italics
- aOnly patients with primary bladder cancer without any neoadjuvant therapy were included
- bLog-rank test at the two-sided significance level of 0.05