Skip to main content

Table 3 Univariate analysis of clinicopathological parameters influencing OS

From: Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer

 

Overall survival (OS)

 

n a

Events

p valueb

Parameter:

 RBBP8 methylationc

  RBBP8 Mlow

262

103

0.039

  RBBP8 Mhigh

85

24

 Gender

  Male

253

91

0.920

  Female

94

36

 Histological tumor graded

  Low grade

15

0

0.066

  High grade

329

127

 Tumor stage

  pT1-pT2

105

23

≤ 0.001

  pT3-pT4

214

94

 pN status

  Negative

207

53

≤ 0.001

  Nositive

111

63

 pM status

  Negative

168

52

0.004

  Positive

7

5

  1. Significant p values are in italics
  2. aOnly patients with primary bladder cancer without any neoadjuvant therapy were included
  3. bLog-rank test at the two-sided significance level of 0.05
Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us