From: Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma
Univariate Analysis | Model 1 | Model 2 | Model 3 | Model 4 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | (95% CI) | p value | HR | (95% CI) | p value | HR | (95% CI) | p value | HR | (95% CI) | p value | HR | (95% CI) | p value | |
miR-122-5p, >cut-off vs. <cut-off | 3.63 | 1.42–9.32 | 0.007 | 2.11 | 0.73–6.11 | 0.169 | 2.34 | 0.77–7.11 | 0.132 | 1.62 | 0.45–5.84 | 0.455 | |||
miR-206, >cut-off vs. <cut-off | 4.98 | 1.95–12.7 | < 0.001 | 3.67 | 1.29–10.51 | 0.015 | 3.46 | 1.13–10.68 | 0.030 | 2.94 | 0.86–10.04 | 0.084 | |||
pT-stage, pT3–4 vs. pT1–2 | 4.14 | 1.59–10.79 | 0.004 | 1.85 | 0.58–5.92 | 0.300 | 2.68 | 0.88–8.21 | 0.082 | 1.94 | 0.60–6.29 | 0.269 | |||
pN-stage, pN1 vs. pN0 | 6.85 | 1.45–32.47 | 0.015 | 4.01 | 0.68–23.72 | 0.125 | 2.72 | 0.49–15.11 | 0.252 | 4.40 | 0.72–27.01 | 0.109 | |||
M-stage, cM1 vs. cM0 | 3.61 | 1.25–10.42 | 0.018 | 1.49 | 0.44–5.01 | 0.521 | 1.18 | 0.34–3.88 | 0.787 | 1.40 | 0.42–4.72 | 0.583 | |||
Fuhrman-Grading, G3 + 4 vs. G1 + 2 | 4.08 | 1.58–10.55 | 0.004 | 1.48 | 0.43–5.18 | 0.536 | 1.65 | 0.48–5.67 | 0.426 | 1.18 | 0.29–4.86 | 0.816 |