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Table 1 Demographic data and clinic characteristics of the IVF patients who participated in the study

From: Aberrant expression and DNA methylation of lipid metabolism genes in PCOS: a new insight into its pathogenesis

Items

Control (n = 119)

PCOS (n = 110)

P value

Age

29.85 ± 0.37

29.11 ± 0.35

0.149

Body mass index

21.74 ± 0.29

22.79 ± 0.36

0.024

Cycle length (days)

29.00 ± 0.22

67.73 ± 6.40

< 0.001

Duration of infertility

4.24 ± 0.30

3.91 ± 0.26

0.416

Fasting glucose (mmol/L)

4.65 ± 0.04

4.75 ± 0.05

0.068

Fasting insulin (pmol/L)*

70.29 ± 2.99

100.19 ± 5.35

< 0.001

HOMA-IR*

2.00 ± 0.09

2.96 ± 0.16

< 0.001

Day 3 LH/FSH

0.72 ± 0.04

1.48 ± 0.09

< 0.001

Day 3 TT (nmol/L)

0.78 ± 0.03

3.02 ± 0.14

< 0.001

Day 3 DHEA-S (μmol/L)

6.61 ± 0.24

7.62 ± 0.33

0.013

Day 3 E2 (pmol/L)

130.69 ± 4.63

148.47 ± 7.96

0.055

AFC

9.92 ± 0.30

20.45 ± 0.39

< 0.001

Androstenedione (ng/ml) in FF#

6.62 ± 1.06

7.25 ± 1.28

0.345

TT (ng/ml) in FF#

4.87 ± 0.49

9.25 ± 1.21

0.022

SHBG (nmol/L) in FF#

57.70 ± 3.01

53.06 ± 3.14

0.042

FAI in FF#

31.63 ± 4.34

69.28 ± 13.81

0.024

Insulin (mU/L) in FF#

37.51 ± 3.13

48.45 ± 3.50

0.024

Retrieved oocyte number

12.58 ± 0.64

17.63 ± 0.89

< 0.001

  1. Values are presented as mean ± SE. P value was determined by Student’s t tests
  2. HOMA-IR homeostasis model assessment of insulin resistance, Day 3 the third day of spontaneous menstrual cycle, LH luteinizing hormone, FSH follicle stimulating hormone, TT total testosterone, DHEA-S dehydroepiandrosterone-sulfate, E 2 estradiol, AFC antral follicle count, FF follicular fluid, SHBG sex hormone binding globulin, FAI free androgen index
  3. *n = 53 in control and n = 50 in PCOS
  4. #n = 50 in control and n = 71 in PCOS
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Clinical Epigenetics

ISSN: 1868-7083

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