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Table 1 Demographic data and clinic characteristics of the IVF patients who participated in the study

From: Aberrant expression and DNA methylation of lipid metabolism genes in PCOS: a new insight into its pathogenesis

Items Control (n = 119) PCOS (n = 110) P value
Age 29.85 ± 0.37 29.11 ± 0.35 0.149
Body mass index 21.74 ± 0.29 22.79 ± 0.36 0.024
Cycle length (days) 29.00 ± 0.22 67.73 ± 6.40 < 0.001
Duration of infertility 4.24 ± 0.30 3.91 ± 0.26 0.416
Fasting glucose (mmol/L) 4.65 ± 0.04 4.75 ± 0.05 0.068
Fasting insulin (pmol/L)* 70.29 ± 2.99 100.19 ± 5.35 < 0.001
HOMA-IR* 2.00 ± 0.09 2.96 ± 0.16 < 0.001
Day 3 LH/FSH 0.72 ± 0.04 1.48 ± 0.09 < 0.001
Day 3 TT (nmol/L) 0.78 ± 0.03 3.02 ± 0.14 < 0.001
Day 3 DHEA-S (μmol/L) 6.61 ± 0.24 7.62 ± 0.33 0.013
Day 3 E2 (pmol/L) 130.69 ± 4.63 148.47 ± 7.96 0.055
AFC 9.92 ± 0.30 20.45 ± 0.39 < 0.001
Androstenedione (ng/ml) in FF# 6.62 ± 1.06 7.25 ± 1.28 0.345
TT (ng/ml) in FF# 4.87 ± 0.49 9.25 ± 1.21 0.022
SHBG (nmol/L) in FF# 57.70 ± 3.01 53.06 ± 3.14 0.042
FAI in FF# 31.63 ± 4.34 69.28 ± 13.81 0.024
Insulin (mU/L) in FF# 37.51 ± 3.13 48.45 ± 3.50 0.024
Retrieved oocyte number 12.58 ± 0.64 17.63 ± 0.89 < 0.001
  1. Values are presented as mean ± SE. P value was determined by Student’s t tests
  2. HOMA-IR homeostasis model assessment of insulin resistance, Day 3 the third day of spontaneous menstrual cycle, LH luteinizing hormone, FSH follicle stimulating hormone, TT total testosterone, DHEA-S dehydroepiandrosterone-sulfate, E 2 estradiol, AFC antral follicle count, FF follicular fluid, SHBG sex hormone binding globulin, FAI free androgen index
  3. *n = 53 in control and n = 50 in PCOS
  4. #n = 50 in control and n = 71 in PCOS