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Table 1 Characteristics of the individuals included in the study

From: TFF1 hypermethylation and decreased expression in esophageal squamous cell carcinoma and histologically normal tumor surrounding esophageal cells

  Healthy subjects* ESCC patients*
Gender
 Male 27 (33%) 50 (78%)
 Female 55 (67%) 14 (22%)
Age (median and range) 58 (20–85) 59 (39–78)
Tobacco smoking
 Never smokers 48 (60%) 1 (3%)
 Former smokers 13 (25%) 6 (17%)
 Current smokers 20 (15%) 29 (81%)
Alcohol drinking
 Never drinkers 41 (50%) 8 (25%)
 Former drinkers 5 (6%) 3 (9%)
 Current drinkers 36 (44%) 21 (66%)
Biopsy localization
 Middle third 88 (100%)  
Tumor localization
 Upper third   2 (3%)
 Upper-middle thirds   4 (6%)
 Middle third   33 (52%)
 Middle-lower thirds   9 (14%)
 Lower third   15 (24%)
Tumor differentiation
 in situ   1 (2%)
 Well   0 (0%)
 Moderate   49 (79%)
 Poor   12 (19%)
T (TNM)   
 Ti   1 (2%)
 T1   8 (14%)
 T2   13 (22%)
 T3   28 (47%)
 T4   9 (15%)
N (TNM)   
 N0   26 (52%)
 N1   24 (48%)
M (TNM)   
 M0   26 (76%)
 M1   8 (24%)
Tumor stage   
 0   1 (3%)
 I   3 (9%)
 II   7 (20%)
 III   16 (46%)
 IV   8 (23%)
  1. *number of patients and controls may vary due to missing data