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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Promoter methylation inhibits expression of tumor suppressor KIBRA in human clear cell renal cell carcinoma

Fig. 1

CpG islands within KIBRA promoter P1a and P1b. The alternative KIBRA promoter system composed of promoter regions P1a, P1b, P2, and P3 and their respective transcription start sites (TSS; right-angled arrows; filled boxes represent exons) located on chromosome 5. Two CpG islands with a length of 205 bp (CpG II, position − 3594/− 3799) and 764 bp (CpG I, position − 1/− 764) within the KIBRA promoter regions P1a and P1b were identified. Of note, Figure S1 contains detailed description of CG dinucleotide rate and positions within CpG islands

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