Table 1 Association of expression levels of miR-335 with clinicopathological features in patients with gastric cancer

N

miR-335 expression (mean ± SD)

p value

Gender

0.531

 Female

15

0.808 ± 0.515

 Male

23

1.246 ± 2.657

Age (years)

0.815

 < 69

19

0.810 ± 0.621

 ≥ 69

19

1.337 ± 2.899

Tumor location

0.107

 Proximal

9

0.987 ± 0.539

 Distal

29

1.100 ± 2.378

Bormann classification

0.148

 I + II

18

1.580 ± 2.962

 III + IV

20

0.618 ± 0.389

WHO classification

0.188

 Tubular

22

0.638 ± 0.399

 Mixed^a

16

1.672 ± 3.136

Histological grade

0.564

 Poor

16

0.655 ± 0.303

 Moderate

22

1.378 ± 2.713

Lauren classification

0.081

 Intestinal

26

1.104 ± 2.504

 Diffuse

12

1.008 ± 0.606

Depth of tumor invasion

0.025*

 T2 + T3

19

1.602 ± 2.865

 T4

19

0.545 ± 0.368

Lymph node metastasis

0.038*

 N0

11

2.060 ± 3.714

 N1 + N2 + N3

27

0.672 ± 0.549

Lymphatic venous and perineural invasion

0.410

 Negative

21

1.355 ± 2.752

 Positive

17

0.725 ± 0.593