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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma

Fig. 5

HOXD10 inhibits cell invasion and migration in HCC cells. a Cell invasion in HOXD10 unexpressed and expressed SMMC7721 and Huh7 cells, as well as in QGY7703 cells before and after knockdown of HOXD10. The number of cell invading to the lower chamber is presented by bar diagram. Each experiment was repeated three times. **P < 0.01, ***P < 0.001. b Cell migration in HOXD10 unexpressed and expressed SMMC7721 and Huh7 cells, as well as in QGY7703 cells before and after knockdown of HOXD10. The migratory cell number is presented by bar diagram. Each experiment was repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001. c The expression levels of HOXD10, MMP2, and MMP9 were detected by western blot

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Clinical Epigenetics

ISSN: 1868-7083

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