Table 1 Patient characteristics (by arm and overall)
Characteristic | All Patients | …in Arm A | …in Arm B |
|---|---|---|---|
Consented | 25 (100%) | 11 (44%) | 14 (56%) |
Randomized and treated | 25 (100%) | 11 (44%) | 14 (56%) |
Evaluable for all study endpoints | 24 (96%) | 10 (40%) | 14 (56%) |
Sex: | |||
 Male | 12 (48%) | 7 (58%) | 5 (42%) |
 Female | 13 (52%) | 4 (31%) | 9 (69%) |
Age, years | |||
 Median (range) | 8.0 (1–16) | 8 (2–16) | 7.5 (1–16) |
Race: | |||
 White | 20 (80%) | 8 (32%) | 12 (48%) |
 African-American | 1 (4%) | 1 (4%) | 0 (0%) |
 Asian | 1 (4%) | 0 (0%) | 1 (4%) |
 American Indian or Alaska native | 1 (4%) | 1 (4%) | 0 (0%) |
 Other | 2 (8%) | 1 (4%) | 1 (4%) |
Ethnicity, Hispanic | 6 (24.0) | Â | Â |
Ethnicity, not Hispanic or Latino | 19 (76.0) | Â | Â |
Cytogenetic risk groups: | |||
 Favorable | 4 (8%) | 1 (4%) | 3 (12%) |
  Intermediate | 17 (68%) | 6 (24%) | 11 (44%) |
 Unfavorable | 4 (16%) | 4 (16%) | 0 (0%) |
Cytogenetics: | |||
 Normal | 7 (28%) | 3 (12%) | 4 (16%) |
 t(8;21) | 4 (16%) | 1 (4%) | 3 (12%) |
 11q23 | 9 (36%) | 5 (20%) | 4 (16%) |
 Other | 5 (20%) | 2 (8%) | 3 (12%) |
Location: | |||
 Alberta (Canada) | 1 (4%) | 1 (4%) | 0 (0%) |
 Children’s Hospital Central California | 1 (4%) | 0 (0%) | 1 (4%) |
 Denver | 8 (32%) | 5 (20%) | 3 (12%) |
 Emory | 1 (4%) | 0 (0%) | 1 (4%) |
 Johns Hopkins | 5 (20%) | 5 (20%) | 0 (0%) |
 John Hunter Hospital (Australia) | 2 (8%) | 0 (0%) | 2 (8%) |
 Mayo Clinic | 1 (4%) | 1 (4%) | 0 (0%) |
 Nationwide Children’s Hospital | 1 (4%) | 0 (0%) | 1 (4%) |
 Phoenix Children’s Hospital | 1 (4%) | 0 (0%) | 1 (4%) |
 Primary Children’s Hospital | 1 (4%) | 0 (0%) | 1 (4%) |
 Royal Children’s Hospital (Australia) | 3 (12%) | 1 (4%) | 2 (8%) |