Table 1 Study cohort for the genome-wide DNA methylation analysis with low versus high maternal pregnancy anxiety (PRAQ): fear of integrity scores
| Â | Low pregnancy anxiety | High pregnancy anxiety | Â | Â |
|---|---|---|---|---|
n = 22 | n = 23 | Test statistic | p value | |
Pregnancy anxiety (PRAQ score) | 2.1 (0.4) | 5.2 (0.7) | t = − 18.906 | p < 0.0001 |
Maternal age (years (SD)) | 30.0 (2.5) | 31.1 (4.0) | t = − 1.115 | 0.27 |
Paternal age (years (SD)) | 32.0 (4.0) | 32.5 (4.6) | t = − 0.397 | 0.69 |
Single parenthood, n (%) | 0 | 1 (4.3%) | Fisher’s exact | 1 |
Method of birth, (n cesarean section (%)) | 2 (9.1%) | 8 (34.8%) | Fisher’s exact | 0.07 |
Maternal BMI before pregnancy (kg/m2) | 23.3 (3.5) | 23.4 (4.3) | t = − 0.478 | 0.64 |
Maternal smoking, n (%) | 2 (9.1) | 0 | Fisher’s exact | 0.23 |
Maternal alcohol use, n (%) | 2 (9.1) | 4 (17.4) | Fisher’s exact | 0.67 |
Gender of the baby, female n (%) | 11 (50) | 10 (43.5) | Chi squared = 0.192 | 0.77 |
Gestational age (days (SD)) | 277.3 (7.2) | 277.1 (10.2) | t = 0.071 | 0.94 |
Birth weight (g (SD)) | 3544.1 (426.1) | 3293.5 (447.2) | t = 1.923 | 0.06 |