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Table 1 Study cohort for the genome-wide DNA methylation analysis with low versus high maternal pregnancy anxiety (PRAQ): fear of integrity scores

From: Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for GABBR1

  Low pregnancy anxiety High pregnancy anxiety   
n = 22 n = 23 Test statistic p value
Pregnancy anxiety (PRAQ score) 2.1 (0.4) 5.2 (0.7) t = − 18.906 p < 0.0001
Maternal age (years (SD)) 30.0 (2.5) 31.1 (4.0) t = − 1.115 0.27
Paternal age (years (SD)) 32.0 (4.0) 32.5 (4.6) t = − 0.397 0.69
Single parenthood, n (%) 0 1 (4.3%) Fisher’s exact 1
Method of birth, (n cesarean section (%)) 2 (9.1%) 8 (34.8%) Fisher’s exact 0.07
Maternal BMI before pregnancy (kg/m2) 23.3 (3.5) 23.4 (4.3) t = − 0.478 0.64
Maternal smoking, n (%) 2 (9.1) 0 Fisher’s exact 0.23
Maternal alcohol use, n (%) 2 (9.1) 4 (17.4) Fisher’s exact 0.67
Gender of the baby, female n (%) 11 (50) 10 (43.5) Chi squared = 0.192 0.77
Gestational age (days (SD)) 277.3 (7.2) 277.1 (10.2) t = 0.071 0.94
Birth weight (g (SD)) 3544.1 (426.1) 3293.5 (447.2) t = 1.923 0.06