Skip to main content

Table 6 Replicated differentially methylated positions (DMPs) associated with WC and abdominal obesity reported by previous EWAS

From: An epigenome-wide association study in whole blood of measures of adiposity among Ghanaians: the RODAM study

     

WC

Abdominal obesity

CpG site

CHR

Position

Nearest gene (distance)a

Featureb

Beta differencec

p valued

FDRd

Beta differencec

p valued

FDRd

cg00574958

11

68607622

CPT1A

5′ UTR

− 0.0007

1.02E − 08

9.87E − 06

−0.0135

1.55E − 08

1.49E − 05

cg04927537

17

76976091

LGALS3BP

TSS200

0.0013

6.74E − 08

3.26E − 05

0.0195

4.44E − 05

1.07E − 02

cg25178683

17

76976267

LGALS3BP

TSS1500

0.0011

3.96E − 07

1.28E − 04

0.0136

1.54E − 05

7.22E − 03

cg07504977

10

102131012

LINC00263 (− 2321)

IGR

0.0010

1.60E − 05

3.87E − 03

0.0240

2.24E − 05

7.22E − 03

cg18335991

15

74724562

SEMA7A

Body

0.0009

2.22E − 05

4.30E − 03

0.0147

3.75E − 04

7.24E − 02

cg27243685

21

43642366

ABCG1

Body

0.0004

7.58E − 05

1.22E − 02

0.0037

1.72E − 02

3.77E − 01

cg10927968

11

1807333

CTSD

IGR

0.0007

9.42E − 05

1.30E − 02

0.0082

1.27E − 02

3.77E − 01

cg06500161

21

43656587

ABCG1

Body

0.0003

2.15E − 04

2.60E − 02

0.0033

3.47E − 03

2.76E − 01

cg13123009

6

31681882

LY6G6E

TSS200

0.0004

3.22E − 04

3.46E − 02

0.0074

3.65E − 03

2.76E − 01

cg17439800

1

208056493

CD34

IGR

0.0006

5.09E − 04

4.92E − 02

0.0205

5.83E − 04

9.39E − 02

  1. aCpGs are located in the gene if no distance is indicated. Distance is expressed in kilobase
  2. bBased on manifest feature annotation Illumina. IGR, intergenic region
  3. cNegative beta values indicate lower DNA methylation (hypo-methylation) in cases compared with controls
  4. d p values and FDR corresponding to M values. Table is sorted on WC associated p values. All significant hits for both outcomes are included
Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us