| | | | | |
WC
|
Abdominal obesity
|
|---|
|
CpG site
|
CHR
|
Position
|
Nearest gene (distance)a
|
Featureb
|
Beta differencec
|
p valued
|
FDRd
|
Beta differencec
|
p valued
|
FDRd
|
|---|
|
cg00574958
|
11
|
68607622
|
CPT1A
|
5′ UTR
|
− 0.0007
|
1.02E − 08
|
9.87E − 06
|
−0.0135
|
1.55E − 08
|
1.49E − 05
|
|
cg04927537
|
17
|
76976091
|
LGALS3BP
|
TSS200
|
0.0013
|
6.74E − 08
|
3.26E − 05
|
0.0195
|
4.44E − 05
|
1.07E − 02
|
|
cg25178683
|
17
|
76976267
|
LGALS3BP
|
TSS1500
|
0.0011
|
3.96E − 07
|
1.28E − 04
|
0.0136
|
1.54E − 05
|
7.22E − 03
|
|
cg07504977
|
10
|
102131012
|
LINC00263 (− 2321)
|
IGR
|
0.0010
|
1.60E − 05
|
3.87E − 03
|
0.0240
|
2.24E − 05
|
7.22E − 03
|
|
cg18335991
|
15
|
74724562
|
SEMA7A
|
Body
|
0.0009
|
2.22E − 05
|
4.30E − 03
|
0.0147
|
3.75E − 04
|
7.24E − 02
|
|
cg27243685
|
21
|
43642366
|
ABCG1
|
Body
|
0.0004
|
7.58E − 05
|
1.22E − 02
|
0.0037
|
1.72E − 02
|
3.77E − 01
|
|
cg10927968
|
11
|
1807333
|
CTSD
|
IGR
|
0.0007
|
9.42E − 05
|
1.30E − 02
|
0.0082
|
1.27E − 02
|
3.77E − 01
|
|
cg06500161
|
21
|
43656587
|
ABCG1
|
Body
|
0.0003
|
2.15E − 04
|
2.60E − 02
|
0.0033
|
3.47E − 03
|
2.76E − 01
|
|
cg13123009
|
6
|
31681882
|
LY6G6E
|
TSS200
|
0.0004
|
3.22E − 04
|
3.46E − 02
|
0.0074
|
3.65E − 03
|
2.76E − 01
|
|
cg17439800
|
1
|
208056493
|
CD34
|
IGR
|
0.0006
|
5.09E − 04
|
4.92E − 02
|
0.0205
|
5.83E − 04
|
9.39E − 02
|
-
aCpGs are located in the gene if no distance is indicated. Distance is expressed in kilobase
-
bBased on manifest feature annotation Illumina. IGR, intergenic region
-
cNegative beta values indicate lower DNA methylation (hypo-methylation) in cases compared with controls
-
d
p values and FDR corresponding to M values. Table is sorted on WC associated p values. All significant hits for both outcomes are included
