| | | | | |
BMI
|
Obesity
|
|---|
|
CpG site
|
CHR
|
Position
|
Nearest gene (distance)a
|
Featureb
|
Beta differencec
|
p valued
|
FDRd
|
Beta differencec
|
p valued
|
FDRd
|
|---|
|
cg00574958
|
11
|
68607622
|
CPT1A
|
5′ UTR
|
− 0.0014
|
1.47E − 07
|
1.42E − 04
|
− 0.0189
|
2.58E − 10
|
2.49E − 07
|
|
cg25178683
|
17
|
76976267
|
LGALS3BP
|
TSS1500
|
0.0019
|
1.20E − 06
|
4.62E − 04
|
0.0195
|
8.51E − 05
|
2.74E − 02
|
|
cg04927537
|
17
|
76976091
|
LGALS3BP
|
TSS200
|
0.0026
|
1.43E − 06
|
4.62E − 04
|
0.0286
|
6.85E − 06
|
3.31E − 03
|
|
cg10927968
|
11
|
1807333
|
CTSD (33351)
|
IGR
|
0.0015
|
2.58E − 05
|
6.24E − 03
|
0.0135
|
2.71E − 04
|
4.15E − 02
|
|
cg17320136
|
5
|
10567905
|
ANKRD33B
|
Body
|
0.0015
|
7.47E − 05
|
1.44E − 02
|
0.0109
|
9.60E − 04
|
1.03E − 01
|
|
cg03345232
|
14
|
92981121
|
RIN3
|
Body
|
0.0022
|
1.29E − 04
|
1.78E − 02
|
0.0193
|
2.08E − 03
|
1.66E − 01
|
|
cg08726900
|
16
|
89550474
|
ANKRD11
|
5′ UTR
|
− 0.0029
|
1.40E − 04
|
1.78E − 02
|
− 0.0237
|
3.85E − 03
|
2.33E − 01
|
|
cg11024682
|
17
|
17730094
|
SREBF1
|
Body
|
0.0009
|
1.52E − 04
|
1.78E − 02
|
0.0119
|
1.80E − 04
|
3.47E − 02
|
|
cg15871086
|
18
|
56526595
|
ZNF532 (− 3466)
|
IGR
|
0.0011
|
1.66E − 04
|
1.78E − 02
|
0.0115
|
1.78E − 04
|
3.47E − 02
|
|
cg18335991
|
15
|
74724562
|
SEMA7A
|
Body
|
0.0019
|
2.19E − 04
|
2.12E − 02
|
0.0175
|
2.24E − 03
|
1.66E − 01
|
|
cg07504977
|
10
|
102131012
|
LINC00263 (− 2321)
|
IGR
|
0.0018
|
2.57E − 04
|
2.26E − 02
|
0.0191
|
8.32E − 04
|
1.01E − 01
|
|
cg27243685
|
21
|
43642366
|
ABCG1
|
Body
|
0.0005
|
4.50E − 04
|
3.46E − 02
|
0.0054
|
2.41E − 03
|
1.66E − 01
|
|
cg17439800
|
1
|
208056493
|
CD34 (− 3390)
|
IGR
|
0.0016
|
4.65E − 04
|
3.46E − 02
|
0.0123
|
2.06E − 02
|
5.38E − 01
|
|
cg06500161
|
21
|
43656587
|
ABCG1
|
Body
|
0.0005
|
5.46E − 04
|
3.77E − 02
|
0.0077
|
3.00E − 04
|
4.15E − 02
|
|
cg03546163
|
6
|
35654363
|
FKBP5
|
5′ UTR
|
0.0019
|
6.96E − 04
|
4.49E − 02
|
0.0181
|
4.18E − 03
|
2.38E − 01
|
-
aCpGs are located in the gene if no distance is indicated. Distance is expressed in kilobase
-
bBased on manifest feature annotation Illumina. IGR, intergenic region
-
cNegative beta values indicate lower DNA methylation (hypo-methylation) in cases compared with controls
-
d
p values and FDR corresponding to M values. Table is sorted on BMI associated p values. All significant hits for both outcomes are included
