Table 2 Correlations between DNA methylation and gene expression of metformin transporter genes in human liver with P value < 0.05 in subjects from the Kuopio Obesity Surgery Study (n = 42)
Probe ID | Chr. | Position | Gene region | r (P value) | q value | B (P value)a |
|---|---|---|---|---|---|---|
SLC22A1 | ||||||
cg05307864 | 6 | 160559487 | Body | 0.408 (0.007) | 0.091 | 0.64 (0.011) |
SLC22A3 | ||||||
cg02042585 | 6 | 160783785 | Body | 0.409 (0.007) | 0.161 | 4.40 (0.010) |
cg06295784 | 6 | 160771074 | Body | − 0.368 (0.016) | 0.184 | − 3.47 (0.026) |
cg17364114 | 6 | 160769359 | TSS200 | 0.320 (0.038) | 0.291 | 2.76 (0.024) |
SLC47A1 | ||||||
cg12799818 | 17 | 19450343 | Body | 0.338 (0.029) | 0.696 | 0.89 (0.036) |