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Table 2 Correlations between DNA methylation and gene expression of metformin transporter genes in human liver with P value < 0.05 in subjects from the Kuopio Obesity Surgery Study (n = 42)

From: Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver

Probe ID Chr. Position Gene region r (P value) q value B (P value)a
SLC22A1
 cg05307864 6 160559487 Body 0.408 (0.007) 0.091 0.64 (0.011)
SLC22A3
 cg02042585 6 160783785 Body 0.409 (0.007) 0.161 4.40 (0.010)
 cg06295784 6 160771074 Body − 0.368 (0.016) 0.184 − 3.47 (0.026)
 cg17364114 6 160769359 TSS200 0.320 (0.038) 0.291 2.76 (0.024)
SLC47A1
 cg12799818 17 19450343 Body 0.338 (0.029) 0.696 0.89 (0.036)
  1. q values are based on false discovery rate (FDR) tests
  2. r correlation coefficient, B regression coefficient
  3. aAdjusted for age, sex, and NASH
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Clinical Epigenetics

ISSN: 1868-7083

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