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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma

Fig. 1

Flow chart indicating study design. We identified candidate CpG sites from 32 paired OSCC and adjacent non-tumor tissues by methylation 450k assay in the discovery set. Then, we excluded a large proportion of CpG sites that were unrelated to survival and developed prognostic scores by SIS. The seven-CpG-based classifier was validated in two independent datasets. Relationships between methylation and gene expression were also analyzed in the training dataset

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Clinical Epigenetics

ISSN: 1868-7083

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