Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome

Table 1 Overall survival of MDS patients with different miR-124 methylation levels at CpG sites by pyrosequencing

mir-124 genes	Cut-off values (%)	No. of patients		Overall survival (months)		P
mir-124 genes	Cut-off values (%)	Low-meth	High-meth	Low-meth	High-meth
miR-124-1	4.9	33	23	31.8	8.4	0.025
miR-124-1-1	3.5	15	41	32.7	11.6	0.034
miR-124-1-2	4.5	15	41	32.7	11.3	0.048
miR-124-1-3	3.5	16	40	21.8	11.6	0.209
miR-124-1-4	8.5	44	12	21.8	5.4	<0.001
miR-124-2	24.8	27	29	31.8	6.6	0.004
miR-124-2-1	11.5	23	33	31.8	11.3	0.125
miR-124-2-2	15	26	30	31.8	6.6	0.020
miR-124-2-3	19.5	35	21	21.8	6.6	0.053
miR-124-2-4	16.5	35	21	31.8	6.2	0.001
miR-124-2-5	30	24	32	32.7	6.6	0.001
miR-124-3	8.6	21	35	32.7	7.6	0.010
miR-124-3-1	6.5	15	41	31.8	12.8	0.117
miR-124-3-2	10.5	29	27	31.8	6.6	0.052
miR-124-3-3	4.5	17	39	23.8	7.7	0.306
miR-124-3-4	14.5	19	37	31.8	11.6	0.094
miR-124-3-5	12	37	19	31.8	6.6	0.004
miR-124-3-6	4.5	20	36	31.8	7.5	0.009
miR-124-3-7	6.5	20	36	31.8	11.3	0.048
miR-124-3-8	11.5	19	37	46.5	7.5	<0.001
miR-124-3-9	8.5	36	20	31.8	6.6	0.026

ISSN: 1868-7083