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Table 1 Overall survival of MDS patients with different miR-124 methylation levels at CpG sites by pyrosequencing

From: Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome

mir-124 genes Cut-off values (%) No. of patients Overall survival (months) P
Low-meth High-meth Low-meth High-meth  
miR-124-1 4.9 33 23 31.8 8.4 0.025
 miR-124-1-1 3.5 15 41 32.7 11.6 0.034
 miR-124-1-2 4.5 15 41 32.7 11.3 0.048
 miR-124-1-3 3.5 16 40 21.8 11.6 0.209
 miR-124-1-4 8.5 44 12 21.8 5.4 <0.001
miR-124-2 24.8 27 29 31.8 6.6 0.004
 miR-124-2-1 11.5 23 33 31.8 11.3 0.125
 miR-124-2-2 15 26 30 31.8 6.6 0.020
 miR-124-2-3 19.5 35 21 21.8 6.6 0.053
 miR-124-2-4 16.5 35 21 31.8 6.2 0.001
 miR-124-2-5 30 24 32 32.7 6.6 0.001
miR-124-3 8.6 21 35 32.7 7.6 0.010
 miR-124-3-1 6.5 15 41 31.8 12.8 0.117
 miR-124-3-2 10.5 29 27 31.8 6.6 0.052
 miR-124-3-3 4.5 17 39 23.8 7.7 0.306
 miR-124-3-4 14.5 19 37 31.8 11.6 0.094
 miR-124-3-5 12 37 19 31.8 6.6 0.004
 miR-124-3-6 4.5 20 36 31.8 7.5 0.009
 miR-124-3-7 6.5 20 36 31.8 11.3 0.048
 miR-124-3-8 11.5 19 37 46.5 7.5 <0.001
 miR-124-3-9 8.5 36 20 31.8 6.6 0.026
  1. Italics are statistically significant