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Fig. 3 | Clinical Epigenetics

Fig. 3

From: CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel

Fig. 3

ROC analysis discriminating OSCC vs normal healthy donors using easyROC as a webtool, showing the three best performing CpGs from GP1BB and ZAP70. Comparing OSCC vs normal healthy donors, these two genes revealed the highest discrimination power: ZAP70 showing hypermethylation and GP1BB showing hypomethylation. ROC analysis of all of the gene targets evaluated in this study is available in Additional file 3

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