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Table 2 Multivariate analysis of factors affecting survival using Cox proportional hazards model in 165 HNSCC patients

From: Epigenetic silencing of SALL3 is an independent predictor of poor survival in head and neck cancer

 

Disease-free survival

Variables

HR (95% CI)

P

Age

 70 and older vs. <70

1.062 (0.659–1.711)

0.8038

Gender

 Male vs. female

1.170 (0.644–2.125)

0.6064

Alcohol exposure

 Ever vs. never

1.015 (0.565–1.823)

0.9606

Smoking status

 Smoker vs. nonsmoker

1.339 (0.752–2.383)

0.3216

Stage

 I, II, III, vs. IV

2.356 (1.480–3.751)

0.0003*

SALL3 methylation

 Yes vs. no

1.914 (1.157–3.164)

0.0114*

  1. HR hazard ratio, 95% CI 95% confidence interval