Fig. 2
From: Epigenetic silencing of SALL3 is an independent predictor of poor survival in head and neck cancer
Pattern of methylation in matched pairs of head and neck tumors and adjacent normal mucosal tissues, and ROC curve analysis of NMV. a SALL3-P1 NMVs of head and neck tumors were higher than those of adjacent normal mucosal tissues (P < 0.001). b Area under the ROC curve (AUROC) for SALL3-P1 was 0.7407. c A higher frequency and degree of SALL3-P2 methylation was observed in head and neck tumors than in matched normal mucosae (P < 0.001). d AUROC value for SALL3-P2 was 0.7863. At the cutoff value of 0.11, sensitivity was 58.3% and specificity was 91.7%. e SALL3-P3 NMVs of head and neck tumors were higher than those of paired adjacent normal mucosae (P < 0.001) f AUROC value for SALL3-P3 was 0.7832