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Table 1 Clinicopathological features of 41 patients diagnosed with papillary thyroid carcinoma

From: Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

Characteristics

Number

Frequency (%)

Age (years)

 Median (interquartile range)

39(20-77)

 

 <55

34

83

 ≥55

7

17

Gender

 Female

30

73

 Male

11

27

Size Tumor (cm)

 Median (range)

1.2(0.6-3.2)

 

mPTC (≤1)

18

44

 PTC (>1)

23

56

Predominant variant

  

 Classic

29

71

 Follicular

7

17

 Othera

3

7

 Not available

2

5

Multicentricity

 No

17

41

 Yes

24

59

Extrathyroidal extension

 No

20

49

 Yes

21

51

Lymph Nodes involvement

 No

25

61

 Yes

16

39

Angiolymphatic invasion

 No

39

95

 Yes

1

5

Perineural invasion

  

 No

36

88

 Yes

2

5

 Not available

3

7

Outcome

 Favorableb

36

88

 Poor c

5

12

Follow-up

 >5 years

36

88

 <5 years

5

12

Somatic alterations

 BRAF mutation

28

68

 BRAF wild-type

13

32

 RAS mutation

0

0

 RAS wild-type

41

100

 RET/PTC inversion

5

12

 RET/PTC wild-type

36

88

  1. mPTC Papillary thyroid microcarcinoma
  2. aThree rare variants were grouped: one tall cells, one oncocytic, and one mucosecretory
  3. bPatients without any suspicion of active disease by imaging scan and/or serum thyroglobulin measurement in at least 5 years of follow-up
  4. cPatients with confirmed recurrent disease in the follow-up