|
Characteristics
|
Number
|
Frequency (%)
|
|---|
|
Age (years)
|
|
Median (interquartile range)
|
39(20-77)
| |
|
<55
|
34
|
83
|
|
≥55
|
7
|
17
|
|
Gender
|
|
Female
|
30
|
73
|
|
Male
|
11
|
27
|
|
Size Tumor (cm)
|
|
Median (range)
|
1.2(0.6-3.2)
| |
|
mPTC (≤1)
|
18
|
44
|
|
PTC (>1)
|
23
|
56
|
|
Predominant variant
| | |
|
Classic
|
29
|
71
|
|
Follicular
|
7
|
17
|
|
Othera
|
3
|
7
|
|
Not available
|
2
|
5
|
|
Multicentricity
|
|
No
|
17
|
41
|
|
Yes
|
24
|
59
|
|
Extrathyroidal extension
|
|
No
|
20
|
49
|
|
Yes
|
21
|
51
|
|
Lymph Nodes involvement
|
|
No
|
25
|
61
|
|
Yes
|
16
|
39
|
|
Angiolymphatic invasion
|
|
No
|
39
|
95
|
|
Yes
|
1
|
5
|
|
Perineural invasion
| | |
|
No
|
36
|
88
|
|
Yes
|
2
|
5
|
|
Not available
|
3
|
7
|
|
Outcome
|
|
Favorableb
|
36
|
88
|
|
Poor c
|
5
|
12
|
|
Follow-up
|
|
>5 years
|
36
|
88
|
|
<5 years
|
5
|
12
|
|
Somatic alterations
|
|
BRAF mutation
|
28
|
68
|
|
BRAF wild-type
|
13
|
32
|
|
RAS mutation
|
0
|
0
|
|
RAS wild-type
|
41
|
100
|
|
RET/PTC inversion
|
5
|
12
|
|
RET/PTC wild-type
|
36
|
88
|
-
mPTC Papillary thyroid microcarcinoma
-
aThree rare variants were grouped: one tall cells, one oncocytic, and one mucosecretory
-
bPatients without any suspicion of active disease by imaging scan and/or serum thyroglobulin measurement in at least 5 years of follow-up
-
cPatients with confirmed recurrent disease in the follow-up
