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Table 4 Significant correlations between changes in biochemical parameters and changes in methylation levels following an n-3 FA supplementation

From: Epigenetic changes in blood leukocytes following an omega-3 fatty acid supplementation

CpG site ID (gene, positiona)

∆Triglyceride

∆TC/HDL-C

∆Glucose

∆cg00011856 (IGFBP5, Chr2:217560946)

0.39 (0.023)b

0.36 (0.042)

–

∆cg05655647 (ATF1, Chr12:51157023)

-0.35 (0.047)

–

–

∆cg24455383 (AKT3, Chr1:243736307)

–

0.42 (0.016)b

–

∆cg15656521 (HDAC4, Chr2:239970617)

–

–

0.35 (0.043)

  1. Results are R (P value)
  2. Abbreviations: HDL-C high-density lipoprotein cholesterol, TC total cholesterol
  3. aAll positions are from the Genome Build 37
  4. bCorrelation remains significant after adjustments for age, sex, and body mass index
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Clinical Epigenetics

ISSN: 1868-7083

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