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Table 2 Summary of methylation results

From: Epigenetic changes in blood leukocytes following an omega-3 fatty acid supplementation

 

n

Probes

485 577

Number of probes detected (P ≤ 0.05)

484 027

 Differentially methylated (FDR-corrected DiffScore ≥ǀ13ǀ)

308

  Hypermethylated after n-3 FA supplementation

286

   Gene body

107

   3′-UTR

34

   1st exon

4

   5′-UTR

19

   Promoter regiona

50

   Intergenic region

72

  Hypomethylated after n-3 FA supplementation

22

   Gene body

5

   3′-UTR

0

   1st exon

1

   5′-UTR

5

   Promoter regiona

6

   Intergenic region

5

  1. Localization according to the first annotated transcript for each CpG site and provided for the Infinium HumanMethylation450 BeadChip
  2. Abbreviations: FDR false discovery rate, UTR untranslated region, TSS transcription start site
  3. aPromoter region includes TSS1500 and TSS200