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Table 4 Top10 CpG sites by biomarker ranking that differentiate subcutaneous and omental adipose tissue at each time point

From: Genome-wide DNA methylation analysis reveals loci that distinguish different types of adipose tissue in obese individuals

Illumina probe ID AB mean beta (±standard deviation) OM mean beta (±standard deviation) UCSC gene namea b CpG site chromosome and positionb Traditional analysis rank by P value Traditional analysis rank by absolute Δbeta
Before weight loss analysis
 cg02245004 0.12 (±0.08) 0.64 (±0.11) Intergenic 15:76634887 318 1
 cg03923561 0.45 (±0.07) 0.04 (±0.02) HOXC4 12:54447220 12 5
 cg22747076 0.42 (±0.09 0.02 (±0.02) HOXC4 12:54447873 31 7
 cg09400037 0.42 (±0.06) 0.82 (±0.07) Intergenic 16:84822801 102 6
 cg24376776 0.03 (±0.01) 0.33 (±0.03) Intergenic 10:101297245 1 62
 cg11797364 0.59 (±0.1) 0.97 (±0.02) Intergenic 6:436969 329 14
 cg17496661 0.65 (±0.08) 0.99 (±0.01) Intergenic 5:3326343 146 28
 cg09720701 0.37 (±0.05) 0.06 (±0.01) HOXC4 12:54447283 7 47
 cg02264990 0.35 (±0.06) 0.03 (±0.02) HOXC4 12:54447243 30 46
 cg01524853 0.43 (±0.05) 0.12 (±0.03) HOXC4 12:54447807 2 51
After weight loss analysis
 cg00838040 0.34 (±0.07) 0.97 (±0.03) ATP2C2 16:84446919 2 1
 cg21917524 0.31 (±0.07) 0.81 (±0.04) Intergenic 11:74200334 19 10
 cg24145118 0.84 (±0.07) 0.31 (±0.16) Intergenic 10:2777041 3554 7
 cg12984729 0.09 (±0.03) 0.59 (±0.16) ISL2 15:76633817 3338 11
 cg12437821 0.46 (±0.04) 0.05 (±0.09) Intergenic 12:114852027 185 48
 cg01184975 0.53 (±0.05) 0.10 (±0.11) Intergenic 12:114852091 567 33
 cg20291855 0.03 (±0.03) 0.44 (±0.11) Intergenic 4:13524143 1994 42
 cg25365014 0.79 (±0.05) 0.41 (±0.05) Intergenic 5:2727713 1 89
 cg16297011 0.07 (±0.04) 0.48 (±0.11) Intergenic 4:13539023 1771 40
 cg21982455 0.56 (±0.04) 0.19 (±0.07) Intergenic 5:2757976 92 86
  1. a‘Intergenic’, no gene loci annotation in Illumina manifest
  2. bGene symbol and map position as Illumina manifest, GRCh37/hg19