Table 3 Significant differential methylation within genes involved in mesothelial lineage and development

Illumina probe ID

CpG site chromosome and position^a

UCSC gene name

Location

AB mean beta

OM mean beta

Δbeta

Adjusted P value

AB mean beta

OM mean beta

Δbeta

Adjusted P value

cg01168289

11:32421514

WT1

Body

0.584

0.745

−0.161

0.030

cg27019929

11:3421518

WT1

Body

0.626

0.845

−0.221

2.1 × 10⁻⁴

cg24325551

11:3421635

WT1

Body

0.502

0.713

−0.211

0.002

0.425

0.665

−0.241

2.1 × 10⁻⁵

cg20449659

11:3421752

WT1

Body

0.594

0.795

−0.201

0.03

0.469

0.751

−0.282

5.7 × 10⁻⁶

cg08575722

11:3421845

WT1

Body

0.36

0.622

−0.262

0.003

cg09695430

11:32447944

WT1

Body

0.326

0.527

−0.2

1.2 × 10⁻⁴

0.259

0.557

−0.298

1.2 × 10⁻⁵

cg20204986

11:32448067

WT1

Body

0.406

0.596

−0.19

0.001

0.314

0.596

−0.281

2.1 × 10⁻⁴

cg13638420

11:32448293

WT1

Body

0.236

0.391

−0.155

0.014

0.195

0.447

−0.253

0.009

cg12006284

11:32449638

WT1

Body

0.303

0.448

−0.145

0.022

cg13540960

11:32450244

WT1

Body

0.082

0.270

−0.188

0.05

cg05222924

11:32450486

WT1

Body

0.072

0.238

−0.166

1.3 × 10⁻⁴

cg19211915

11:32452513

WT1

Body

0.183

0.250

−0.067

0.03

cg09234616

11:32452592

WT1

Body

0.074

0.203

−0.129

0.025

cg08079266

16:817098

MSLN

Body

0.877

0.922

−0.045

0.03

cg04476874

19:345778

MIER2

TSS1500

0.527

0.735

−0.208

2.7 × 10⁻⁵

Illumina probe ID

CpG site chromosome and position^a

UCSC gene name

Location

AB mean beta

OM mean beta

Δbeta

Merit score

AB mean beta

OM mean beta

Δbeta

Merit score

cg05069835

7:76139338

UPK3B

TSS1500

0.49

0.557

−0.067

0.006

cg24325551

11:3421635

WT1

Body

0.502

0.713

−0.211

0.109

cg10244666

11:3421808

WT1

Body

0.639

0.357

0.282

0.130

cg08575722

11:3421845

WT1

Body

0.479

0.648

−0.169

0.035

cg20204986

11:32448067

WT1

Body

0.406

0.596

−0.19

0.086

cg13638420

11:32448293

WT1

Body

0.447

0.195

0.252

0.147

cg12006284

11:32449638

WT1

Body

0.506

0.274

0.232

0.074

cg04456238

11:32450104

WT1

0.301

0.437

−0.136

0.025

0.481

0.251

0.23

0.069

cg13540960

11:32450244

WT1

0.082

0.27

−0.188

0.099

cg05222924

11:32450486

WT1

0.316

0.091

0.225

0.099

cg06516124

11:32450591

WT1

0.089

0.184

−0.095

0.017

cg09234616

11:32452592

WT1

0.074

0.203

−0.129

0.049

cg15315385

11:32452839

WT1

0.27

0.169

0.101

0.016

cg04130356

16:810643

MSLN

TSS1500

0.686

0.789

−0.103

0.04

cp0838005

16:816149

MSLN

Body

0.946

0.883

0.063

0.006

cg08581018

16:832942

MSLNL

TSS200

0.621

0.722

−0.101

0.015

cg16804923

16:834399

MSLNL

TSS1500

0.838

0.898

−0.06

0.012

0.861

0.756

0.105

0.029

cg04476874

19:345778

MIER2

TSS1500

0.735

0.527

0.208

0.134