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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study

Fig. 1

Analysis workflow. Differentially methylated genes were detected using a single CpG and a region-based approach. Only sig-DMPs and sig-DMRs were selected in which the pesticide exposed QR carrier group was either hyper- or hypomethylated in comparison with the other groups (interesting profile). By overlapping the sig-DMPs with the sig-DMRs a high confidence list of differentially methylated genes could be generated

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