Table 6 Top diseases and biological functions associated with differentially methylated genes between COPD vs. non-smokers
From: DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD
Diseases and disorders | P value | No. of molecules |
Organismal injury and abnormalities | 7.91E-03–1.41E-04 | 40 |
Cancer | 7.91E-03–1.53E-04 | 32 |
Connective tissue disorders | 7.91E-03–3.69E-04 | 8 |
Dermatological diseases and conditions | 7.91E-03–5.12E-04 | 13 |
Respiratory disease | 7.91E-03–5.43E-04 | 9 |
Molecular and cellular functions | P value | No. of molecules |
Cellular development | 7.91E-03–3.40E-10 | 58 |
Cell death and survival | 7.91E-03–1.55E-07 | 49 |
Cell morphology | 7.91E-03–3.15E-07 | 43 |
Cellular assembly and organization | 7.91E-03–3.15E-07 | 32 |
Cellular function and maintenance | 7.91E-03–3.15E-07 | 44 |
Physiological system development and function | P value | No. of molecules |
Nervous system development and function | 7.91E-03–3.33E-09 | 49 |
Tissue morphology | 7.91E-03–2.60E-07 | 49 |
Tissue development | 7.91E-03–3.15E-07 | 56 |
Organ morphology | 7.91E-03–4.93E-07 | 32 |
Organismal development | 7.91E-03–4.93E-07 | 60 |