Table 3 Top 10 differentially methylated CpG sites in COPD compared to non-smokers, sorted by P value
From: DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD
CpG site | Gene symbol | Chromosome | aProbe Type | P value | bGene location of first annotated transcript | Island location |
|---|---|---|---|---|---|---|
cg05275153 | RGS12 | 4 | I | 2.24E-06 | Body | Â |
cg06746365 | PRKAG2 | 7 | II | 2.48E-06 | Body | Â |
cg08830492 | NFASC | 1 | I | 1.24E-06 | 5UTR | Island |
cg14630106 | HIPK2 | 7 | II | 3.35E-06 | Body | Â |
cg15558717 | CAV1 | 7 | II | 2.40E-06 | Body | Â |
cg22837763 | ANGPT1 | 8 | II | 1.30E-07 | Body | Â |
cg22920586 | PLD1 | 3 | II | 5.93E-07 | 5UTR | Â |
cg24408769 | JARID2 | 6 | I | 3.30E-06 | Body | Â |
cg25010400 | MECOM | 3 | II | 3.64E-06 | Body | Â |
cg25383568 | ACTN4 | 19 | I | 1.75E-06 | Body | Island |