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Table 2 Multiple linear regression model for all DNA sources as well as PBMC, normal colorectal mucosa, and CRC tumour DNA

From: The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer

  All DNA sources PBMC Normal colon Tumour
Variable r P r P r P r P
Tissue 0.06 0.07       
rs1800734 −0.07 0.045 −0.14 0.02 −0.15 0.01 0.03 0.58
Age 0.07 0.05 −0.05 0.28 0.19 0.001 0.04 0.36
Sex 0.0002 0.78 0.06 0.47 0.003 0.77 −0.04 0.54
Stage −0.01 0.79 0.11 0.07 0.13 0.04 −0.14 0.02
MSI status 0.03 0.93 0.05 0.48 0.04 0.91 0.01 0.70
MLH1 CpG island methylation −0.03 0.49 −0.02 0.60 −0.02 0.57 −0.04 0.39
  1. Significant results are italicized
  2. The Pearson correlation (r) and P value for each variable are described