Fig. 1From: The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancerMean percent methylated reference (PMR) of the MLH1 shore. MethyLight was utilized to determine PMR in PBMC, normal colorectal tissue, and colorectal tumour DNA of 349 population-based CRC cases. All cases were genotyped for SNP rs1800734. There were 211 wildtype (GG), 119 heterozygous (GA), and 19 homozygous variant (AA) carriers. a Mean MLH1 shore methylation in each DNA source. b Mean MLH1 shore methylation in each DNA source stratified by genotype of rs1800734. c Mean MLH1 shore methylation for each genotype of rs1800734 stratified by DNA source. *P < 0.05 and **P < 0.01Back to article page