Skip to main content

Table 2 Cox proportional hazards survival models including mdNLR, age, grade, and tumor mutation status

From: Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival

  

n deceased

Survival years

Univariate models

Multivariate model

Number

Mean

Median

HR (95% CI)

p value

HR (95% CI)

p value

mdNLR < 4

mdNLR > = 4

44

28

35

23

4.8

3.1

4.3

1.8

Referent group

1.78 (1.03–3.07)

0.038

Referent group

2.02 (1.11–3.69)

0.022

GBM

non-GBM

33

39

32

26

2.9

5.3

1.7

5.3

Referent group

0.48 (0.28–0.81)

0.006

Referent group

1.06 (0.56–2.00)

0.859

IDH only

TERT only

30

42

18

40

6.6

2.4

7.2

1.4

4.19 (2.34–7.48)

<0.0001

referent group

4.83 (2.35–9.93)

0.00002

Age (continuous)

     

0.97 (0.92–1.02)

0.274

  1. All covariates modeled met proportionality assumptions
  2. HR hazard ratio, CI confidence interval
  3. MdNLR methylation-derived NLR (neutrophil to lymphocyte ratio)