Table 2 Validation of differentially methylated regions
Methylation status in 450K array | Overlap with CGI | Gene | No. of samples | No. of concordant samples | % of concordant samples |
|---|---|---|---|---|---|
Hypermethylated | CGI | ZNF577 | 53 | 42 | 79.25 |
HLA-DPB1 | 51 | 38 | 74.51 | ||
LHX1 | 53 | 41 | 77.36 | ||
MYH14 | 13 | 11 | 84.62 | ||
Non-CGI | ZSCAN31 | 47 | 35 | 74.47 | |
LDLRAD4 | 53 | 37 | 69.81 | ||
LXN | 53 | 37 | 69.81 | ||
Hypomethylated | CGI | PIWIL1 | 14 | 13 | 92.86 |
MFAP2 | 11 | 9 | 81.82 | ||
Non-CGI | PTPN22 | 53 | 33 | 62.26 | |
SPNS3 | 14 | 10 | 71.43 | ||
AIM2 | 12 | 10 | 83.33 | ||
SLAMF1 | 12 | 8 | 66.67 | ||
SPATA13 | 10 | 7 | 70.00 |