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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Improved results of LINE-1 methylation analysis in formalin-fixed, paraffin-embedded tissues with the application of a heating step during the DNA extraction process

Fig. 1

a DNA preparation of mouse xenograft tissue samples (n = 10) and human archival tissue samples (gastric cancer (GC), n = 476; colorectal cancer (CC), n = 497). Each xenograft tumor tissue was cut into five slices. Each slice was treated using five different formalin fixation protocol. b Both heat-treated and heat-untreated DNA samples were subjected to bisulfite conversion and subsequent pyrosequencing methylation assay or MethyLight assay

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Clinical Epigenetics

ISSN: 1868-7083

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