Table 3 Associations between genome-wide DNA methylation and lipid levels (meta-analyses)
From: Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study
Model 2a | Model 3b | Model 4c | ||||||
|---|---|---|---|---|---|---|---|---|
ProbeID | Regression coefficient | p d | Regression coefficient | p d | Regression coefficient | p d | Gene | |
TG | cg00574958 | −0.0142 | 2.6 × 10 −26 | −0.0114 | 1.9 × 10 −16 | −0.0161 | 1.5 × 10 −22 | CPT1A |
cg06500161 | 0.0167 | 1.4 × 10 −24 | 0.0153 | 3.9 × 10 −18 | 0.0151 | 7.0 × 10 −14 | ABCG1 | |
cg11024682 | 0.0147 | 3.0 × 10 −19 | 0.0124 | 8.4 × 10 −13 | 0.0138 | 1.0 × 10 −11 | SREBF1 | |
cg17058475 | −0.0146 | 3.1 × 10 −13 | −0.0120 | 8.8 × 10 −09 | −0.0196 | 9.2 × 10 −16 | CPT1A | |
cg17901584 | −0.013 | 1.9 × 10 −08 | −0.0104 | 2.5 × 10 −05 | −0.012 | 2.5 × 10 −05 | DHCR24 | |
HDL-C | cg06500161 | −0.0187 | 9.5 × 10 −23 | −0.0166 | 9.5 × 10 −16 | −0.0116 | 2.5 × 10 −07 | ABCG1 |
cg14816825 | −0.0104 | 3.2 × 10 −07 | −0.0145 | 3.8 × 10 −07 | −0.0127 | 1.7 × 10 −07 | NA e | |
cg17901584 | 0.0164 | 2.4 × 10 −09 | 0.0128 | 1.3 × 10 −05 | 0.0116 | 3.6 × 10 −04 | DHCR24 | |