Fig. 1

a Heatmap of DNA methylation state of the 432 bladder cancer-specific MVPs from the discovery cohort: tumour in red (n = 86) and normal urothelium in blue (n = 30). b Heatmap of the 150 loci defined in the UroMark assay: non-cancer urine in light blue (n = 10), normal urothelium in dark blue (n = 30), bladder cancer in red (n = 86) and blood in green (n = 489). The heatmap colour scale depicts methylation values ranging from 0% (yellow) to 100% (blue)