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Table 1 TET and IDH gene mutation analysis in 218 CLL patients

From: Characterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance

Position/mutation Type Consequence
TET1
 chr10:g.70318749T>A Single base substitution Upstream
 chr10:g.70333015C>A Single base substitution Missense: P307H
 chr10:g.70413592G>A Single base substitution Intron
 chr10:g.70346080G>A Single base substitution Intron
 chr10:g.70447656G>A Single base substitution Intron
 chr10:g.70360941C>G Single base substitution Intron
TET2
 chr4:g.106161089G>A Single base substitution 3 UTR | intron
 chr4:g.106196355C>T Single base substitution Missense: S1563F, S1584F | 3 UTR
 chr4:g.106175952A>C Single base substitution Intron
 chr4:g.106075153G>A Single base substitution Intron
 chr4:g.106108570A>T Single base substitution Intron
 chr4:g.106087334A>C Single base substitution Intron
 chr4:g.106064903T>A Single base substitution Upstream: AC004069.2
TET3
 chr2:g.74276067C>A Single base substitution Downstream | intron
 chr2:g.74226519->A Insertion of ≤200 bp Upstream
 chr2:g.74300784G>A Single base substitution Exon | intron
 chr2:g.74247963G>A Single base substitution Intron
 chr2:g.74274651G>A Single base substitution Missense: R443H, R401H | Exon
 chr2:g.74238478A>T Single base substitution Intron
 chr2:g.74278374G>A Single base substitution Downstream
IDH1
 chr2:g.209111428G>A Single base substitution Downstream | intron
 chr2:g.209123819C>T Single base substitution Upstream | downstream IDH1-AS1| intron
 chr2:g.209135430A>G Single base substitution Upstream-AC016697.2 | intron: PIKFYVE
 chr2:g.209121002T>G Single base substitution Upstream | downstream: IDH1-AS1 | intron
 chr2:g.209102172T>C Single base substitution Upstream: AC016697.3 | intron
IDH2
 chr15:g.90631755C>T Single base substitution Intron
 chr15:g.90631061C>A Single base substitution Intron