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Table 3 Mean number of hypermethylated genes in each group

From: Cell-free DNA promoter hypermethylation in plasma as a diagnostic marker for pancreatic adenocarcinoma

Group N Mean number of methylated genes 95% CI p value
Pancreatic cancer 95 8.41 (7.62–9.20)  
Control group 1; screened negative 27 4.89 (4.07–5.71)  
Control group 2; chronic pancreatitis 97 4.34 (3.85–4.83)  
Control group 3; acute pancreatitis 59 5.34 (4.77–5.91)  
Control groups 1 + 2 124 4.46 (4.04–4.88) <0.0001a
Control groups 1 + 2 + 3 183 4.74 (4.40–5.08) <0.0001b
  1. The means were compared as numerical data with nonparametric Wilcoxon rank sum test. p values less than 0.05 were considered statistically significant
  2. aSignificant difference between patients with pancreatic cancer and control groups 1 + 2
  3. bSignificant difference between patients with pancreatic cancer and control groups 1 + 2 + 3
  4. CI confidential interval