Cohort | Comparison | Significance level | Expected probability | Probability estimate | Binomial test P value |
---|---|---|---|---|---|
GenRED Offspring Saliva, cortisol | Neuron, suicide | 0.05 | 0.507 | 0.614 | 3.47 × 10−102 |
0.01 | 0.158 | 0.242 | 8.70 × 10−28 | ||
0.001 | 0.019 | 0.026 | 0.332 | ||
GenRED Offspring Blood, cortisol | Neuron, suicide | 0.05 | 0.470 | 0.569 | 2.97 × 10−86 |
0.01 | 0.132 | 0.209 | 1.30 × 10−26 | ||
0.001 | 0.015 | 0.039 | 9.71 × 10−3 | ||
Combined GenRED Offspring Blood and saliva, cortisol | Neuron, suicide | 0.05 | 0.522 | 0.618 | 1.68 × 10−81 |
0.01 | 0.187 | 0.251 | 1.34 × 10−15 | ||
0.001 | 0.032 | 0.035 | 0.851 | ||
Houtepen et al. [20] Cortisol | Neuron, suicide | 0.05 | 0.470 | 0.578 | 2.01 × 10−105 |
0.01 | 0.119 | 0.193 | 6.02 × 10−32 | ||
0.001 | 0.011 | 0.029 | 3.15 × 10−3 | ||
Combined GenRED Offspring Blood and saliva, cortisol | Houtepen et al. [20] Cortisol | 0.05 | 0.522 | 0.603 | 6.70 × 10−60 |
0.01 | 0.187 | 0.264 | 1.08 × 10−25 | ||
0.001 | 0.032 | 0.061 | 4.96 × 10−3 |