Fig. 2
From: Maternal vitamin D depletion alters DNA methylation at imprinted loci in multiple generations
Maternal (G0) vitamin D deficiency is linked to (G1) offspring developmental outcomes. a G1 male 8 weeks body weight (N = 24, 24, 31, 25). b G1 male 8 weeks percent lean (left y-axis, open bars) and fat mass (right x-axis, closed bars) (N = 3, 10, 5, 6). c Combined testes weight (N = 24, 17, 29, 17, upper panel) and testes weight corrected for body weight (N = 22, 17, 29, 14, bottom panel). d Total sperm count (N = 25, 17, 29, 15). Each dot represents an individual sample. Error bars represent standard error of the mean. Asterisks (*) or (***) indicate p value <0.05 or 0.005 determined by t test within each cross; panel above each graph lists all statistically significant (p value <0.05) comparisons determined by regression analysis for overall diet-dependent effects (diet), diet-independent parent of origin effects (PO), and diet-dependent parent of origin effects (diet × PO). n.s. not significant