Fig. 2
From: Epigenetic signature of Gleason score and prostate cancer recurrence after radical prostatectomy
Epigenetic signature of Gleason score and prostate cancer recurrence in the Fred Hutchinson cohort. a Recurrence-free survival by quartiles (Q1–4) of the epigenetic signature. The vertical dashed line shows the recurrence-free survival rate at 10 years after diagnosis. b The signature improved the prediction of recurrence beyond the standard clinical-pathological parameters: Gleason score, pathological stage, and diagnostic PSA level (likelihood-ratio (LR) test, P < 0.05). c, d Same analyses as in Fig. 2a, b, but for all patients with Gleason score 7 tumors. e–f Same analyses as in Fig. 2a, b, but for patients with Gleason score 7(3 + 4) tumors