Table 1 Differentially expressed genes in patients with ANCA-associated vasculitis compared to healthy controls regulating histone post-translational modifications and DNA methylation

MSL3

207551_s_at

male-specific lethal 3 homolog

0.0002

1.65

MSL1

224765_at

male-specific lethal 1 homolog

<0.0001

1.60

KAT8

221820_s_at

lysine acetyltransferase 8

0.0187

1.38

BRD4

226052_at

bromodomain containing 4

0.0003

1.38

ING4

218234_a

inhibitor of growth family, member 4

<0.0001

−2.05

MLL3

222415_at

myeloid/lymphoid or mixed-lineage leukemia 3

<0.0001

1.53

MLL2

231974_at

myeloid/lymphoid or mixed-lineage leukemia 2

0.0003

1.51

MLL4

203419_at

myeloid/lymphoid or mixed-lineage leukemia 4

0.0107

1.26

RTF1

212302_at

Rtf1, Paf1/RNA polymerase II complex component

0.0409

1.24

BCOR

223566_s_at

BCL6 corepressor

<0.0001

−1.74

KDM1A

212348_s_at

lysine-specific demethylase 1A

0.0002

−1.57

C14orf169

219526_at

lysine-specific demethylase NO66

0.0002

−1.34

BRD4

226052_at

bromodomain containing 4

0.0003

1.38

NSD1

225654_at

nuclear receptor binding SET domain protein 1

0.0208

1.34

BCOR

223566_s_at

BCL6 corepressor

<0.0001

−1.74

C14orf169

219526_at

lysine-specific demethylase NO66

0.0002

−1.34

EHMT1

222873_s_at

euchromatic histone-lysine N-methyltransferase 1

0.0084

−1.41

EHMT2

202326_at

euchromatic histone-lysine N-methyltransferase 2

0.0013

−1.44

ARID4B

212591_at

AT rich interactive domain 4B (RBP1-like)

<0.0001

−1.51

ARID4B

212591_a

AT rich interactive domain 4B (RBP1-like)

<0.0001

−1.51

DNMT1

201697_s_at

DNA (cytosine-5-)-methyltransferase 1

<0.0001

−2.03