Fig. 2From: Genetic and epigenetic mechanisms in the development of arteriovenous malformations in the brain a Schematic representation of how aberrant hemodynamic forces cause altered arteriovenous shunting and further develops into AVM. b The altered blood forces may result in aberrant epigenetic landscape with possibility of hypo- or hyper-DNA methylations and alterations of various histone modifications and lead to AVMBack to article page