From: Combinatorial epigenetic therapy in diffuse large B cell lymphoma pre-clinical models and patients
 | All patients (n = 18) | |
---|---|---|
Characteristic | Number | % |
Gender | ||
 Male | 11 | 61 |
 Female | 7 | 39 |
Age in years | ||
 Median (range) | 66.5 (27–83) | |
ECOG | ||
 0 | 0 | 0 |
 1 | 10 | 55.6 |
 2 | 8 | 44.4 |
Histological diagnosis | ||
 DLBCL | 15 | 83.3 |
 Transformed FL | 2 | 11.1 |
 CLL with Richter’s transformation | 1 | 5.5 |
Prior treatments regimens | ||
 Median (range) | 3 (1–4) | |
 Rituximab-containing | 18 | 100 |
 Autologous stem cell transplantation | 3 | 16.7 |
Response to prior line of therapy | ||
 CR | 4 | 22.2 |
 PR | 1 | 5.6 |
 Refractory | 13 | 72.2 |