Fig. 3From: Genome-wide placental DNA methylation analysis of severely growth-discordant monochorionic twins reveals novel epigenetic targets for intrauterine growth restrictionDNAm changes in IUGR twins in ZNF300 promoter. Methylation levels in IUGR twins (orange circles) and unaffected co-twins (blue crosses) are shown, arranged vertically for each CpG in the region spanning the promoter of the ZNF300 gene transcript. The mean methylation levels are shown for the IUGR cohort (red line) and controls (blue line). The top seven CpGs with methylation change above 10Â % comprise the DMR (red box), which also corresponds to the wider gap between the red and blue lines Back to article page