Fig. 1
From: Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus
Biological and technical confounders contribute to DNA methylation value variations. The heatmap displays significant correlations for each covariate. The –log10 p values of the linear regressions of the top ten principal components onto each known covariate are shown. The color key shows corresponding numeric values, with darker color indicating increased significance. Proteinuria, maximum systolic blood pressure, and magnesium sulfate treatment are contributing to the DNA methylation variability